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• About CRC
• Centre de Recherche des Cordeliers
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• Research
• Departments
• Department 1: Physiology, Metabolism
• Molecular Oral Pathophysiology
• Metabolic Diseases, Diabetes and co-morbidities
• Physiopathology of ocular diseases: therapeutic innovations
• Renal physiology and tubulopathies
• Department 2: Immunology and Cancer
• Health data- and model- driven Knowledge Acquisition (HeKA)
• Laboratory of Integrative Cancer Immunology
• Inflammation, Complement and Cancer
• Metabolism, cancer and immunity
• Immunopathology and therapeutic immuno-intervention
• Department 3: Genome and Cancer
• Oncogenic functions of β-catenin signaling in the liver (ONCOLIV)
• Personalized medicine, pharmacogenomics, therapeutic optimization : MEPPOT
• Functional Genomics of Solid Tumors (FUNGEST)
• Proliferation Stress and Liver Physiopathology
• Drug resistance in hematological malignancies (DRIHM)
• Ethics, research, translation: ETRES
• CRC teams
• Bacterial structures involved in modulation of antibiotic resistance
  Michel Arthur
• Physiopathology of ocular diseases: therapeutic innovations
  
  Francine Behar-Cohen
• Mechanisms regulating tissue transparency
• Neuroprotection
• Biomarkers and drug delivery
• Molecular Oral Pathophysiology
  
  Ariane Berdal
• POM – Main original and review publications (2015-2020)
• Rare Oral Diseases
• Gene-Environment relationships
• Oncogenic functions of B-catenin signaling in the liver
  
  Sabine Colnot
• Oncogenic functions of Beta-catenin signaling in the liver (ONCOLIV)
• Early steps of liver carcinogenesis
• Oncometabolism
• Epigenetics and resistance to immunotherapies
• Renal physiology and tubulopathies
  
  Gilles Crambert
• Renal physiology and tubulopathies
• Salt homeostasis and its disorders
• Potassium homeostasis and its disorders
• Divalent cation homeostasis and its disorders
• Genetic and translational research on tubulopathies
• Kidney function investigation facility
• Inflammation, Complement and Cancer
  Isabelle Cremer
• Inflammation, Complement and Cancer
• INFLAMMATION AND CANCER
• Immunotherapy and Cancer
• Complement in physiology and pathology
• Proliferation stress and liver physiopathology
  Chantal Desdouets
• Proliferation stress and liver physiopathology (ProLiverPP)
• Polyploidy / DNA damage response and liver metabolic disorders
• Polyploidy and consequences on tumor outcome
• Immune microenvironment and liver tumorigenesis
• Metabolic Diseases, Diabetes and co-morbidities
  Fabienne Foufelle
• Metabolic Diseases, Diabetes and co-morbidities
• Non Alcoholic Fatty liver diseases and type 2 diabetes
• Mineralocorticoid Receptor : role in renal and metabolic co-morbidities and therapeutic implications
• Role of sphingolipid metabolism in the development of type 2 diabetes
• Laboratory of Integrative Cancer Immunology
  Jérôme Galon
• Metabolism, Cancer and Immunity
  
  Guido Kroemer
• Immunopathology and therapeutic immuno-intervention.
  Sébastien Lacroix-Desmazes
• Regulatory functions of normal IgG and regulatory T cells in physiopathology.
• Cofactor-binding antibodies
• Immunogenicity of protein therapeutics
• Personalized medicine, pharmacogenomics, therapeutic optimization (MEPPOT)
  Pierre Laurent-Puig
• Personalized Medicine and Pharmacogenomics Group
• Translational research and Microfluidics
• Reprogramming of mitochondrial metabolism in the CMS subtypes of colon cancer
• Cell stress responses in acute and chronic kidney injuries
• The Biological Resource Center (BRC EPIGENETEC)
• Ethics, research, translation (ETRES)
  
  Marie-France Mamzer
• Translational Research
• Care Practices
• Drug resistance in hematological malignancies (DRIHM)
  Santos A. Susin
• Genetic alterations associated with drug resistance in agressive forms of CLL and Waldenstrom’s macroglobulinemia
• The immune repertoire of B-cell malignancies
• Metabolic specificities in chronic lymphocytic leukemia: towards the design of a new therapeutic approach
• New therapeutic approaches for mastocytosis
• Intraocular and cerebral lymphomas
• Health data- and model- driven Knowledge Acquisition (HeKA)
  Sarah Zohar
• Patient phenotyping and representation learning
• Stochastic and data-driven predictive modelling of health trajectories
• Designs of next generation clinical trials
• Functional Genomics of Solid Tumors (FUNGEST)
  Jessica Zucman-Rossi
• Computational Cancer Genome Analysis
• Functional Genomics of Mesothelioma
• Core facilities
• Core facilities
• CHIC
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• Functional Exploration Center (CEF)
• Genotyping and biochemical center (CGB)
• L2 & L3 Laboratories
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• Immunity and metabolism of diabetes
• Transcriptomics & Epigenomics
• Bioenergetics
• Immunoregulation of pancreatic islets
• Integrative data science
• Clinical science

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